منابع مشابه
Modelling HIV-1 2-LTR dynamics following raltegravir intensification
A model of reservoir activation and viral replication is introduced accounting for the production of 2-LTR HIV-1 DNA circles following antiviral intensification with the HIV integrase inhibitor raltegravir, considering contributions of de novo infection events and exogenous sources of infected cells, including quiescent infected cell activation. The model shows that a monotonic increase in meas...
متن کاملLqg/ltr Controller Design for Rotary Inverted Pendulum Quanser Real-time Experiment
This experiment consists of a rigid link (pendulum) rotating in a vertical plane. The rigid link is attached to a pivot arm, which is mounted on the load shaft of a DC-motor. The pivot arm can be rotated in the horizontal plane by the DC-motor. The DC-motor is instrumented with a potentiometer. In addition, a potentiometer is mounted on the pivot arm to measure the pendulum angle. The principal...
متن کاملOptimization of SiC particle distribution during compocasting of A356-SiCp composites using D-optimal experiment design
This paper presents an experimental design approach to the process parameter optimization for compocasting of A356-SiCp composites. Toward this end, parameters of stirring temperature, stirring time, stirring speed and SiC content were chosen and three levels of these parameters were considered. The D-optimal design of experiment (DODE) was employed for experimental design and analysis of resul...
متن کاملTranscriptional modulation of HIV-1C LTR promoter
Background All current anti-HIV1 therapies target the viral proteins or RNA; however targeting HIV1 at the transcriptional level of the integrated provirus has been less explored. In India, AIDS is commonly caused by HIV-1C compared to HIV-1B in developed countries. HIV1-5’LTR acts as a promoter and shows sequence variation among different clades. Transcriptional gene silencing (TGS) is a metho...
متن کاملExon2 of HIV-2 Tat contributes to transactivation of the HIV-2 LTR by increasing binding affinity to HIV-2 TAR RNA.
Human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) express related Tat proteins that are encoded in two exons. Tat proteins bind directly to the TAR RNA element contained in the 5' ends of viral transcripts and thereby stimulate transcription through an as yet unidentified mechanism. We have investigated the functional significance of exon2 of the HIV-2 Tat protein by examining proper...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0206700